Minkyu Kim
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Associate Professor of Materials Science and Engineering
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Associate Professor of Biomedical Engineering
Dr. Kim is an associate professor in the Department of Materials Science and Engineering and the Department of Biomedical Engineering at the University of Arizona from Fall 2016.
He earned his B.S. in Mechanical Engineering from Kyung Hee University in February 2004. During his undergraduate study, he was recognized with a silver award (2nd prize) at the 14th National Undergraduate Student Competition in Transport Phenomena held by the Korean Institute of Chemical Engineers and graduated with a Dean’s award for his academic achievements.
Dr. Kim moved to the U.S. for his graduate work, where he earned an M.S. in Biomedical Engineering in December 2006 and a Ph.D. in Mechanical Engineering and Materials Science in May 2011 at Duke University. He was a recipient of fellowships from the Korea Science and Engineering Foundation, Pratt School of Engineering at Duke University and Medtronic Foundation. Under the guidance of Prof. Marszalek, his research focused on biopolymer (proteins, DNA) design, synthesis, mechanics and self-assembly for nanostructured molecular materials. He discovered a unified structure-mechanical property relationship that elucidates the spring-like behavior found in most α-helical spiral-shaped proteins at the nanoscale level. He also developed a potential fabrication method to hierarchically self-assemble these mechanical proteins into supramolecular structures. His research was recognized with several awards from Duke University, including the Student Research Achievement Award at the Biophysical Society annual meeting in 2010.
After finishing his doctoral studies, Dr. Kim started his postdoctoral research with Prof. Olsen at MIT. His research focused on the development of biopolymer-based functional materials for defense applications. He developed a formulation where self-associated polymeric nanomaterials effectively detoxify chemical warfare nerve agents for environmental decontamination. He also designed the first synthetic selective filtering biopolymer hydrogel inspired by the nuclear membrane for the development of novel selective filtering materials to detect and remove biological warfare agents, such as SEB, anthrax and botulinum.
Dr. Kim’s research interests are broadly clustered in the areas of bioinspired/biomimetic materials, biomolecular engineering, soft condensed matter physics and nanoscale biophysics. He is currently interested in how bioinspired design and biosynthesis can be used for the preparation of novel functional materials, how the nanomechanics of folded biopolymers and artificially engineered hyperbranched biopolymer structures can be translated into the mechanics of macromolecular materials that provide new insight into polymer physics, and how protein sequences can control parameters that regulate the functional properties of polymeric materials. The developed materials will target applications in biotechnology for improving healthcare and national defense.
Degrees
- Ph.D. Mechanical Engineering and Materials Science
- Duke University, Durham, North Carolina, United States
- Design and characterization of protein-based building blocks for constructing self-assembled nanostructured molecular networks and materials
- M.S. Biomedical Engineering
- Duke University, Durham, North Carolina, United States
- B.S. Mechanical Engineering
- Kyung Hee University, Suwon, Korea, Republic of
Work Experience
- University of Arizona, Tucson, Arizona (2023 - Ongoing)
- Yonsei University (2019 - Ongoing)
- University of Arizona, Tucson, Arizona (2016 - 2023)
- Massachusetts Institute of Technology, Cambridge, Massachusetts (2012 - 2016)
- Duke University, Durham, North Carolina (2006 - 2012)
Interests
Teaching
Synthetic and biological Materials (MSE/BME 461/561), Biomaterial-Tissue Interactions (BME/ABE 486/586),Research Methods in Biomedical Research (BME 597G)
Research
Functional proteins, artificial protein design, polymer networks, polymer gels, self-assembly, bioinspired/biomimetic materials
Courses
Intro Material Science
MSE 222 (Fall 2024)
Materials Processing Lab
MSE 223L (Spring 2024)
MSE 223L (Spring 2023)
MSE 223L (Spring 2022)
MSE 223L (Spring 2021)
MSE 223L (Spring 2020)
MSE 223L (Spring 2019)
MSE 223L (Spring 2018)
MSE 223L (Spring 2017)
Independent Study
BME 299 (Spring 2019)
BME 499 (Spring 2024)
BME 499 (Fall 2023)
BME 499 (Summer I 2023)
MSE 399 (Fall 2023)
MSE 399 (Spring 2021)
MSE 499 (Spring 2023)
MSE 499 (Spring 2022)
MSE 499 (Spring 2021)
MSE 499 (Fall 2019)
MSE 599 (Spring 2023)
Honors Independent Study
BME 299H (Spring 2022)
BME 299H (Spring 2021)
MSE 399H (Spring 2018)
Biological+Synthetic Mat
BME 461 (Fall 2023)
BME 461 (Fall 2022)
BME 461 (Fall 2021)
BME 461 (Fall 2020)
BME 461 (Fall 2019)
BME 561 (Fall 2023)
BME 561 (Fall 2022)
BME 561 (Fall 2021)
BME 561 (Fall 2020)
BME 561 (Fall 2019)
BME 561 (Fall 2018)
BME 561 (Fall 2016)
MSE 461 (Fall 2023)
MSE 461 (Fall 2022)
MSE 461 (Fall 2021)
MSE 461 (Fall 2020)
MSE 461 (Fall 2019)
MSE 461 (Fall 2018)
MSE 461 (Fall 2016)
MSE 561 (Fall 2023)
MSE 561 (Fall 2022)
MSE 561 (Fall 2021)
MSE 561 (Fall 2020)
MSE 561 (Fall 2018)
Biomat-Tissue Interactns
ABE 486 (Spring 2018)
ABE 486 (Spring 2017)
ABE 586 (Spring 2018)
ABE 586 (Spring 2017)
BE 486 (Spring 2024)
BE 486 (Spring 2023)
BE 486 (Spring 2022)
BE 486 (Spring 2021)
BE 486 (Spring 2020)
BE 486 (Spring 2019)
BME 486 (Spring 2024)
BME 486 (Spring 2023)
BME 486 (Spring 2022)
BME 486 (Spring 2021)
BME 486 (Spring 2020)
BME 486 (Spring 2019)
BME 486 (Spring 2018)
BME 486 (Spring 2017)
BME 586 (Spring 2024)
BME 586 (Spring 2023)
BME 586 (Spring 2022)
BME 586 (Spring 2021)
BME 586 (Spring 2020)
BME 586 (Spring 2018)
BME 586 (Spring 2017)
Directed Research
BME 492 (Spring 2024)
BME 492 (Spring 2023)
BME 492 (Fall 2022)
BME 492 (Spring 2022)
BME 492 (Fall 2021)
BME 492 (Summer I 2021)
BME 492 (Spring 2021)
BME 492 (Fall 2020)
BME 492 (Spring 2020)
BME 492 (Fall 2019)
BME 492 (Spring 2019)
BME 492 (Fall 2018)
BME 492 (Fall 2017)
Directed Rsrch
MCB 492 (Fall 2021)
Senior Capstone
MSE 498 (Spring 2023)
MSE 498 (Fall 2022)
MSE 498 (Spring 2021)
MSE 498 (Fall 2020)
MSE 498 (Spring 2020)
MSE 498 (Fall 2019)
Rsrch Meth Biomed Engr
BME 592 (Fall 2023)
BME 592 (Spring 2022)
BME 592 (Fall 2021)
BME 592 (Spring 2021)
BME 597G (Fall 2019)
BME 597G (Fall 2018)
BME 597G (Fall 2017)
BME 597G (Fall 2016)
Biomedical Engr Seminar
BME 696A (Fall 2019)
BME 696A (Fall 2018)
Bme Student Forum
BME 696C (Spring 2020)
BME 696C (Spring 2019)
Research
BME 900 (Spring 2022)
BME 900 (Fall 2020)
BME 900 (Spring 2020)
MSE 900 (Fall 2023)
MSE 900 (Spring 2023)
MSE 900 (Fall 2022)
MSE 900 (Fall 2019)
MSE 900 (Spring 2019)
MSE 900 (Fall 2018)
MSE 900 (Spring 2018)
MSE 900 (Fall 2017)
Master's Report
BME 909 (Spring 2022)
BME 909 (Fall 2021)
Thesis
BME 910 (Spring 2019)
BME 910 (Fall 2018)
Dissertation
BME 920 (Fall 2023)
BME 920 (Spring 2023)
BME 920 (Fall 2022)
BME 920 (Spring 2022)
BME 920 (Fall 2021)
BME 920 (Spring 2021)
BME 920 (Fall 2020)
BME 920 (Spring 2020)
BME 920 (Fall 2019)
BME 920 (Spring 2019)
BME 920 (Fall 2018)
MSE 920 (Spring 2024)
MSE 920 (Fall 2023)
MSE 920 (Spring 2021)
MSE 920 (Fall 2020)
MSE 920 (Spring 2020)
MSE 920 (Fall 2019)
MSE 920 (Spring 2019)
Selected Publications
Journals/Publications
- Kim, S., Cathey, M., Bounds, B. C., Scholl, Z., Marszalek, P. E., & Kim, M. (2024). Ligand-Mediated Mechanical Enhancement in Protein Complexes at Nano- and Macro-Scale. ACS Applied Materials & Interfaces, 16(1), 272-280.
- Doole, F. T., Camp, C. P., & Kim, M. (2023). Tailoring the formation and stability of self-assembled structures from precisely engineered intrinsically disordered protein polymers: A comprehensive review. Giant, 14, 100158.
- Knoff, D. S., Kim, S., Fajardo, C., Rivera, J., Cathey, M., Altamirano, D., Camp, C., & Kim, M. (2022). Non-Covalently Associated Streptavidin Multi-Arm Nanohubs Exhibit Mechanical and Thermal Stability in Cross-Linked Protein-Network Materials. Biomacromolecules, 23(10), 4130-4140.
- Lee, T., Camp, C. P., Kim, B., & Kim, M. (2022). Environmentally Friendly Methylcellulose Blend Binder for Hydrophobic Dust Control. ACS Applied Polymer Materials, 4(2), 1512-1522.
- Wang, Y., Kegel, L. L., Knoff, D. S., Deodhar, B. S., Astashkin, A. V., Kim, M., & Pemberton, J. E. (2022). Layered supramolecular hydrogels from thioglycosides. Journal of Materials Chemistry B, 10(20), 3861-3875.
- Ghandi, J., Heinlich, L., Knoff, D. S., Kim, M., & Marmorstein, A. D. (2021). Alteration of Fibrin Hydrogel Gelation and Degradation Kinetics through Addition of Azo Dyes. Journal of Biomedical Materials Research: Part A.
- Camp, C. P., Peterson, I. L., Knoff, D. S., Melcher, L. G., Maxwell, C. J., Cohen, A. T., Wertheimer, A. M., & Kim, M. (2020). Non-cytotoxic Dityrosine Photocrosslinked Polymeric Materials With Targeted Elastic Moduli. Frontiers in Chemistry, 8, 173.
- Knoff, D. S., Szczublewski, H., Altamirano, D., Fajardo, C., & Kim, M. (2020). Cytoskeleton-Inspired Artificial Protein Design to Enhance Polymer Network Elasticity. Macromolecules, 53(9), 3464-3471.
- Lee, T., Kim, S., Kim, S., Kwon, N., Rho, S., Hwang, D. S., & Kim, M. (2020). Environmentally Friendly Methylcellulose-Based Binders for Active and Passive Dust Control. ACS Applied Materials & Interfaces, 12(45), 50860-50869.
- Lee, T., Park, J., Knoff, D. S., Kim, K., & Kim, M. (2019). Liquid amphiphilic polymer for effective airborne dust suppression. RSC ADVANCES, 9(68), 40146-40151.
- Park, J., Kim, K., Lee, T., & Kim, M. (2019). Tailings Storage Facilities (TSFs) Dust Control Using Biocompatible Polymers. MINING METALLURGY & EXPLORATION, 36(4), 785-795.
- Kim, M., Chen, W. G., Souza, B. S., & Olsen, B. D. (2017). Selective Biomolecular Separation System Inspired by the Nuclear Pore Complex and Nuclear Transport. Molecular Systems Design & Engineering, 2, 149-158. doi:10.1039/C7ME00006E
- Wang, R., Sing, M. K., Avery, R. K., Souza, B. S., Kim, M., & Olsen, B. D. (2016). Classical Challenges in the Physical Chemistry of Polymer Networks and the Design of New Materials. ACCOUNTS OF CHEMICAL RESEARCH, 49(12), 2786-2795.
- Kim, M., Chen, W. G., Kang, J. W., Glassman, M. J., Ribbeck, K., & Olsen, B. D. (2015). Artificially Engineered Protein Hydrogels Adapted from the Nucleoporin Nsp1 for Selective Biomolecular Transport. Advanced materials (Deerfield Beach, Fla.), 27(28), 4207-12.
- Kim, M., Gkikas, M., Huang, A., Kang, J. W., Suthiwangcharoen, N., Nagarajan, R., & Olsen, B. D. (2014). Enhanced activity and stability of organophosphorus hydrolase via interaction with an amphiphilic polymer. Chemical communications (Cambridge, England), 50(40), 5345-8.
Poster Presentations
- Camp, C. P., & Kim, M. (2023, Apr). Elastic Modulus of Engineered Polymeric Hydrogel Materials Modulated by Sequence-Controlled Protein Polymers. 2023 MRS Spring meeting. San Francisco, CA: NSF.
- Grinnell, D., Pershing, H., Maier, R. M., Hogan, D. E., & Kim, M. (2023). Efficacy of Bioinspired Green Glycolipids as Dust Suppressants in Mine Tailings. NIEHS Superfund Research Program Annual Meeting.
- Kim, S. Y., Cathey, M., Bounds, B., Marszalek, P. E., & Kim, M. (2023, Apr). Biopolymer Design that Translates Single-Molecule Protein Nanomechanics to Macroscale Mechanical Properties of Polymer-Network Materials. 2023 MRS Spring Conference. San Francisco, CA: NSF.
- Lee, S., Kim, B., Grove, T. Z., Van Dyke, M. E., & Kim, M. (2023, Apr). Recombinant Keratins Coating for Enhanced Skin-Implant Interface. 2023 MRS Spring meeting. San Francisco, CA: CDMRP.
- Noh, Y. H., & Kim, M. (2023, Apr). Bioinspired Stiffness-Controlled Protein Filaments based on Understanding Hydrodynamics and Molecular Self-Assembly of Constitutive Proteins. 2023 MRS Spring meeting. San Francisco, CA: NSF.
- Wang, Y., Kegel, L. L., Knoff, D. S., Deodhar, B., Kim, M., & Pemberton, J. (2021, October). Layered Supramolecular Hydrogels from Thioglycosides. 2021 The Rocky Mountain Regional Meeting, ACS. Tucson, AZ.
- Deodhar, B., Knoff, D., Kim, M., & Pemberton, J. (2021, October). Glyonic Liquids: Green Ionic Liquids Manufactured from Sustainable Glycolipids. 2021 The Rocky Mountain Regional Meeting, ACS. Tucson, AZ.
- Doole, F. T., Chan, C. K., Kim, M., Singharoy, A., & Brown, M. F. (2021, Feb). Antimicrobial Peptide-Membrane Interactions: Insights from Molecular Simulations. 65th Annual Meeting of the Biophysical Society. Online.
- Doole, F., Chan, C., Streitwieser, E., Sarkar, D., Kim, M., Struts, A., Singharoy, A., & Brown, M. F. (2021, October). Solid-state NMR spectroscopy and molecular simulations reveal antimicrobial peptide biomembrane interactions. 2021 The Rocky Mountain Regional Meeting, ACS. Tucson, AZ.
- Kim, M. (2021, April). Cytoskeleton-Inspired Biopolymer Design for Reduced Polymer Network Defects Towards Constructing Biomimetic Nonlinear-Elastic Materials. 2021 ACS Spring meeting. Online.
- Doole, F. T., Chan, C. K., Kim, M., Singharoy, A., & Brown, M. F. (2020, Feb). Antimicrobial Peptide Functionalized Biomaterials Investigated by Molecular Dynamics Simulations. 64th Annual Meeting of the Biophysical Society. San Diego, CA.
- Melcher, L. G., Doole, F. T., Camp, C. P., Peterson, I. L., Kim, M., & Wertheimer, A. M. (2020, June). Antimicrobial Properties of Artificial Polypeptide-based Materials. 2020 American Society for Microbiology. Chicago, IL.
- Camp, C. P., Li, Z., Peterson, I., Doole, F. T., Kim, M., & Wertheimer, A. M. (2019, May). Novel Wound Healing Thermoresponsive Biomatrix with Antimicrobial and Anti-Inflammatory Properties. 8th International Symposium on the Diabetic Foot. Hague, Netherlands.
- Lee, T., Knoff, D. S., & Kim, M. (2019, March). Liquid Amphiphilic Polymer for Enhanced Airborne Dust Suppression. ACS Spring Meeting. Orlando, FL.
- Knoff, D. S., & Kim, M. (2018, Apr). Ligand-Mediated Mechanical Reinforcement of Injectable Protein Hydrogels. MRS Spring meeting. Phoenix, AZ.
Presentations
- Kim, M. (2023, Apr). Design of Artificial Protein Polymers for Healthcare Materials. 2023 MRS Spring Conference. San Francisco, CA: NSF.
- Kim, M. (2023, Feb). Artificial Protein Polymers for Multifunctional Materials. Civil & Architectural Engineering & Mechanics, University of Arizona, Tucson, AZ. Tucson: University of Arizona.
- Kim, M. (2023, Oct). Design of Erythrocyte-Inspired Polymeric Materials for Advanced Healthcare. ASU Biomaterials Day, Society for Biomaterials. Phoenix, AZ.
- Kim, M., Maier, R. M., Lee, T., Rodriguez, C., Martinez, F., Grinnell, D., & Hogan, D. E. (2023). Tailings Dust Control Using Bioinspired Glycolipid Surfactants. Society for Mining, Metallurgy, and Exploration Annual Conference. Denver, CO.
- Kim, M. (2021, April). Design of Mechanosensitive Polymeric Materials Inspired by Red Blood Cell. Department seminar. Online, Tim Taylor Department of Chemical Engineering, Kansas State University.
- Kim, M. (2022, January). Functional Biopolymeric Materials. Seminar. Online - SungKyunKwan University.
- Camp, C. P., Knoff, D. S., Doole, F. T., & Kim, M. (2021, April). Mechanical properties of engineered hydrogel materials modulated by sequence-controlled protein polymers. 2021 ACS spring meeting. Online.
- Doole, F. T., Melcher, L. G., Camp, C. P., Wertheimer, A. M., Singharoy, A., Brown, M. F., & Kim, M. (2021, April). Artificial Protein Design as an Effective Material Platform for Antimicrobial Peptides. 2021 MRS Spring meeting. Online.
- Kim, M. (2021, April). Artificial protein design rules to harness protein tertiary structures for polymeric materials with exotic mechanical behaviors. 2021 MRS Spring meeting. Online.
- Kim, M. (2021, May). Environmentally-Friendly Polymer Formulations for Dust Control in Mining Industry. UA Superfund Colloquium Seminar. Online - University of Arizona.
- Kim, M. (2021, September). Design of Mechanosensitive Polymeric Materials Inspired by Red Blood Cell. Department Seminar. ”, Department of Aerospace and Mechanical Engineering, the University of Arizona.
- Kim, M. (2020, June). Genetically Engineered Biopolymer Materials to Mitigate Infectious Diseases. Yonsei University. Seoul, Korea.
- Kim, M. (2019, Apr). Development of Polymer Formulations to Control (Ultra)Fine Dust in Subway Tunnel. Seminar. Seoul Metro, the City of Seoul, Korea.
- Kim, M. (2019, Nov). Controlling a Dust in a Dry World. College of Engineering. College of Engineering, University of Arizona: Tech Launch Arizona.
- Kim, M. (2019, Nov). Design of Mechanosensitive Polymeric Materials Inspired by Red Blood Cell Mechanics. Seminar. Department of Chemistry and Biochemistry, University of Arizona.
Awards
- NSF CAREER Award
- National Science Foundation, Fall 2021
- Award for Excellence at the Student Interface
- College of Engineering, University of Arizona, Spring 2018
- College of Engineering, University of Arizona, Spring 2017